Browsing by Author "Dankel, Simon N"

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    • Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue 

      Meen, Astri Jeanette; Doncheva, Atanaska Ivanova; Böttcher, Yvonne; Dankel, Simon N; Hoffmann, Anne; Blüher, Matthias; Fernø, Johan; Mellgren, Gunnar; Ghosh, Adhideb; Sun, Wenfei; Dong, Hua; Noé, Falko; Wolfrum, Christian; Pejler, Gunnar; Dalen, Knut Tomas; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-07)
      Proteoglycans are central components of the extracellular matrix (ECM) and binding partners for inflammatory chemokines. Morphological differences in the ECM and increased inflammation are prominent features of the white adipose tissues in patients with obesity. The impact of obesity and weight loss on the expression of specific proteoglycans in adipose tissue is not well known. This study aimed to ...

    • Relationship between Ketones, Ghrelin, and, Appetite on Isocaloric Diets with Varying Carbohydrate Quality and Amount: Results from a Randomized Controlled Trial in People with Obesity (CARBFUNC) 

      Horn, Cathrine; Gjerde, Eirin Semb; Laupsa-Borge, Johnny; Andersen, Amanda Iselin Olesen; Lawrence-Archer, Laurence; McCann, Adrian; Hansson, Patrik; Raza, Ghulam S.; Herzig, Karl Heinz; Lied, Gülen Arslan; Alho Letra Martins, Catia Patricia; Mellgren, Gunnar; Dierkes, Jutta; Dankel, Simon N (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-29)
      Background - Low-carbohydrate high-fat (LCHF) diets may suppress the increase in appetite otherwise seen after diet-induced fat loss. However, studies of diets without severe energy restriction are lacking, and the effects of carbohydrate quality relative to quantity have not been directly compared.<p> <p>Objectives - To evaluated short- (3 mo) and long-term (12 mo) changes in fasting plasma ...